Cancer recurrence tests, in-body 3D printing, and AI voice restoration
Plus 20 new health tech job opportunities
Oh hey there 👋
Here’s what’s inside this week’s newsletter:
🧬 Exact Sciences develops a new test to detect cancer recurrence years earlier than imaging
🪄 Researchers use ultrasound and 3D printing to deliver treatment directly inside the body without surgery
🗣️ Whispp — a company that has built AI technology to restore natural voices for people with speech disorders
🐣 A womb-lining test offers hope to women with recurrent miscarriage
🔍 20 new job opportunities in health tech
Enjoy! 😊
Company of the Week
Exact Sciences launches a new test to detect cancer recurrence earlier and more accurately
Even after cancer treatments, like chemotherapy or radiation, tiny residual tumor molecules — called molecular residual disease (MRD) — can still be present in the patient’s bloodstream. Research has shown that patients with these molecules are 50 times more likely to experience cancer recurrence than those with no detection.
To address this, Exact Sciences has launched Oncodetect — a new test designed to sensitively detect and monitor MRD across multiple solid tumors.
Oncodetect is tumor-informed, meaning it tailors its analysis to each patient's specific cancer profile, and can identify signs of recurrence up to two years earlier than imaging — making it one of the most precise tools for early detection of recurrence.
This is a major milestone in cancer care, giving clinicians a much more accurate test to detect and monitor MRD, thus improving the chances of catching cancer recurrence earlier.
"After surgery and definitive therapy, the risk for cancer recurrence remains a major concern. Advanced detection tools like the Oncodetect test help bridge that gap by providing clinical insights at critical periods, leading to more informed treatment decisions and personalised care.” — Brian Baranick, Executive Vice President at Exact Sciences
Beyond its diagnostic power, Oncodetect reflects a broader shift toward personalised, precision oncology. Oncodetect could soon become a routine part of post-treatment cancer care, in the hope of giving patients more clarity and control in the fight against cancer.
For more info about Exact Sciences check out:
Oncodetect™ Molecular Residual Disease test — Exact Sciences
Exact Sciences plans 'transformative year' with 3 cancer test debuts — Fierce Biotech
Lessons of the Week
1. Scientists use sound waves to 3D print treatments inside the body without surgery
Scientists have developed a way to treat diseases inside the body without surgery by using 3D printing and ultrasound.
A special liquid is injected directly into the affected organ, then focused ultrasound waves are used to harden the liquid into a solid structure. This structure stays in place and can release medicine over time right at the disease site.
Normally, making a 3D implant requires printing it outside the body and surgically inserting it. But with this method, you can inject the material, then use ultrasound to build the implant directly inside without cutting the body open.
A team at Caltech tested this method by printing soft, medicine-filled gels inside the bladders of mice. The printed gel delivered chemotherapy directly to bladder tumors and killed more cancer cells than simply injecting the drug in liquid form — this shows promise for being a much less invasive and more effective way to administer treatment in the body.
2. AI-powered voice technology by Whispp transforms communication for people with voice disorders
Whispp is a Dutch startup using AI to help people with voice disorders (like severe stuttering, vocal cord paralysis, or post-cancer voice loss) speak more fluently.
Instead of converting speech to text and back again (which causes delays), Whispp uses real-time audio-to-audio AI to turn whispers into the user’s natural-sounding voice on phone, video, or in-person calls.
“I got cancer and lost the ability to communicate well with my grandkids. But fortunately, since I discovered Whispp, I’m now back to being able to tell dad jokes.” — Roger Gillespie, laryngeal cancer patient and Whispp user.
3. UK scientists develop a new test to help women facing recurrent miscarriage
UK scientists have developed a test to identify abnormalities in the womb lining that can increase the risk of miscarriage.
Unlike most research that focuses on embryos, this test looks at whether the womb is properly preparing to support pregnancy.
In a pilot at Tommy’s Centre for Miscarriage Research, the test helped diagnose issues in women with repeated pregnancy loss — some of whom later had successful pregnancies after treatment.
“These findings pave the way not only for an explanation in some cases but more importantly for treatments that could prevent future pregnancy losses.” — Dr Jyotsna Vohra, Director of Research, Programmes and Impact at Tommy’s
Health Tech Jobs of the Week
🇺🇸 US
💻 Healthcare Integration Engineer
Prenosis | $110,000–$150,000 | Remote
Join a small but well-funded team using AI biomarkers to drive precision medicine in acute care.🧩 Head of Partnerships & Growth
Isaac Health | Remote
Drive growth in dementia care through partnerships at a brain health-focused company.💃 Associate Product Manager
Elektra Health | Remote
Join a mission-led startup focused on access and equity in women’s health.🧠 Director of AI Transformation
Aledade | Remote
Build GenAI tools to support independent primary care practices.🎨 Experienced Product Designer
Volta Health | Remote
Set design direction at a startup improving patient care via thoughtful design.📈 Strategic Growth Director
Aidoc | United States
Drive AI-powered radiology adoption and strategy at a leader in medical imaging analysis.💬 Member Engagement Strategy Manager
Spring Health | $98K–$122K | New York (Hybrid)
Shape engagement strategy at a unicorn mental health platform backed by $467M in funding.🚀 Director of Implementation & Strategy
Covera Health | $140K–$160K | New York, NY
Lead strategic rollouts at a precision radiology company improving diagnostic accuracy.💼 Senior Manager, Digital Workplace & IT Ops
Prime Medicine | Cambridge, MA
Oversee workplace IT operations at a gene editing company with $385M raised.🧪 Senior Director / VP Operations
Xaira | $215K–$325K | Brisbane, CA
Drive operations at a $2B unicorn using AI to revolutionize drug discovery.🚁 Materials Program Manager, Platform 2
Zipline | $125K–$155K | South San Francisco, CA
Manage hardware supply chains at a $4B drone company delivering medical supplies globally.🧬 Senior Benefits Program Manager
Altos Labs | $210K–$285K | San Francisco Bay Area, CA
Lead benefits programs at a $3B startup focused on cellular rejuvenation and longevity.🔄 Sr. Project Manager and Scrum Master
Twist Bioscience | $129K–$188K | South San Francisco, CA
Manage biotech software projects at a public synthetic DNA company valued at $2B.
🇬🇧 UK
💌 Senior CRM Executive
Hertility | UK (Remote) | £40K–£50K
Lead lifecycle comms at a CQC-approved startup redefining hormone and fertility care.🧬 People Ops & Experience Manager
Isomorphic Labs (Alphabet) | London
Shape people experience at DeepMind’s drug discovery spin-out.
🌎 Global
🧪 Head of Operations
Daye | Sofia, Bulgaria
Scale ops at a fast-growing femtech innovator making diagnostic tampons mainstream.🧩 Head of Partner Operations
Doctolib | Berlin, Germany
Lead operational partnerships at Europe’s top healthtech scale-up.💰 (Senior) Ops Manager – Financial Products
Nelly | Berlin, Germany
Launch and manage fintech tools supporting patient health services.🧠 Director of Product Operations
Aidoc | Tel Aviv (Remote)
Scale product ops at a global AI radiology leader.🌍 Generalist - Corporate, Product & Ops (14 roles)
Clipboard Health | Remote (Canada, LATAM, Europe)
Multiple openings at a $1.3B platform transforming healthcare staffing.
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I’m always open to featuring health tech companies, new research, or job opportunities in future editions. And if you’ve got thoughts, questions, or spot a mistake, don’t hesitate to reach out — this newsletter is very much a work in progress!
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See you next week 👋